| 09/03/05 | hosting | Central Oklahoma | 37-49 |
| 09/10/05 | at | Northeastern St OK | 20-14 |
| 09/17/05 | hosting | TAMU-Commerce | 27-18 |
| 09/24/05 | hosting | Eastern New Mexico | 30-33 |
| 10/01/05 | at | SE Oklahoma St | 24-42 |
| 10/08/05 | at | Angelo St | 24-27 |
| 10/15/05 | hosting | West Texas A&M | 24-40 |
| 10/22/05 | at | Tarleton St | 18-7 |
| 10/29/05 | hosting | TAMU-Kingsville | 19-3 |
| 11/05/05 | at | Midwestern St | 30-35 |