| 09/03/05 | at | Tennessee | 10-17 |
| 09/10/05 | at | Troy | 27-7 |
| 09/17/05 | hosting | Jacksonville State | 35-28 |
| 10/01/05 | hosting | Rice | 45-26 |
| 10/08/05 | hosting | SMU | 27-28 |
| 10/15/05 | at | Marshall | 19-20 |
| 10/21/05 | hosting | Southern Miss | 28-37 |
| 11/01/05 | at | Memphis | 37-20 |
| 11/12/05 | hosting | Central Florida | 21-27 |
| 11/19/05 | at | UTEP | 35-23 |
| 11/26/05 | at | East Carolina | 23-31 |