| 08/27/05 | at | Concordia-St Paul | 30-33 |
| 09/03/05 | at | Northern St SD | 17-16 |
| 09/10/05 | hosting | SW Minnesota St | 45-3 |
| 09/17/05 | hosting | Minnesota-Crookston | 47-0 |
| 09/24/05 | at | North Dakota | 3-52 |
| 10/01/05 | hosting | South Dakota | 17-48 |
| 10/08/05 | at | St Cloud St | 7-34 |
| 10/15/05 | at | Nebraska-Omaha | 24-50 |
| 10/22/05 | hosting | Minnesota-Duluth | 26-23 |
| 10/29/05 | hosting | Minn St-Mankato | 25-24 |
| 11/05/05 | at | Upper Iowa | 54-6 |