| 09/03/05 | hosting | Central IA | 24-25 |
| 09/10/05 | at | Catholic | 52-26 |
| 09/24/05 | hosting | UW-Platteville | 45-14 |
| 10/01/05 | hosting | North Park | 50-6 |
| 10/08/05 | at | Carthage | 7-0 |
| 10/15/05 | hosting | Illinois Wesleyan | 41-15 |
| 10/22/05 | at | Millikin | 23-0 |
| 10/29/05 | hosting | Elmhurst | 64-42 |
| 11/05/05 | hosting | North Central | 20-17 |
| 11/12/05 | at | Wheaton | 28-7 |
| 11/19/05 | hosting | Lakeland | 49-22 |
| 11/26/05 | at | Mount Union | 7-44 |