| 09/03/05 | at | Minot St | 42-17 |
| 09/10/05 | hosting | Minn St-Mankato | 28-23 |
| 09/17/05 | at | UW-River Falls | 35-19 |
| 09/24/05 | at | Concordia-St Paul | 48-55 |
| 10/01/05 | hosting | SW Minnesota St | 47-9 |
| 10/08/05 | at | Winona St | 13-47 |
| 10/15/05 | at | Minnesota-Crookston | 40-14 |
| 10/22/05 | hosting | Northern St SD | 45-33 |
| 10/29/05 | hosting | Minn St-Moorhead | 27-13 |
| 11/05/05 | vs. | Wayne St NE | 28-38 |