| 09/03/05 | hosting | Colorado State | 31-28 |
| 09/10/05 | hosting | New Mexico State | 39-0 |
| 09/24/05 | at | Miami FL | 3-23 |
| 10/01/05 | at | Oklahoma State | 34-0 |
| 10/08/05 | hosting | Texas A&M | 41-20 |
| 10/15/05 | at | Texas | 17-42 |
| 10/22/05 | hosting | Kansas | 44-13 |
| 10/29/05 | at | Kansas St | 23-20 |
| 11/05/05 | hosting | Missouri | 41-12 |
| 11/12/05 | at | Iowa State | 16-30 |
| 11/25/05 | hosting | Nebraska | 3-30 |
| 12/03/05 | vs. | Texas | 3-70 |
| 12/27/05 | vs. | Clemson | 10-19 |