| 09/03/05 | at | East Carolina | 21-24 |
| 09/10/05 | hosting | Virginia Tech | 0-45 |
| 09/17/05 | hosting | VMI | 40-14 |
| 09/24/05 | at | Virginia | 7-38 |
| 10/01/05 | hosting | Navy | 21-28 |
| 10/08/05 | at | Miami FL | 7-52 |
| 10/15/05 | hosting | Georgia Tech | 10-35 |
| 10/22/05 | hosting | Florida State | 24-55 |
| 10/29/05 | hosting | Wake Forest | 6-44 |
| 11/05/05 | at | Clemson | 20-49 |
| 11/19/05 | at | North Carolina | 21-24 |