| 09/01/05 | at | Indiana State | 24-13 |
| 09/10/05 | at | Brigham Young | 10-45 |
| 09/17/05 | hosting | Illinois St | 6-27 |
| 09/24/05 | hosting | Samford | 43-14 |
| 10/08/05 | at | SE Missouri St | 48-24 |
| 10/15/05 | hosting | Eastern Kentucky | 53-22 |
| 10/22/05 | at | Murray State | 35-28 |
| 10/29/05 | hosting | Tennessee-Martin | 26-7 |
| 11/05/05 | at | Tennessee State | 27-3 |
| 11/12/05 | hosting | Tennessee Tech | 31-20 |
| 11/19/05 | at | Jacksonville State | 10-6 |
| 11/26/05 | hosting | Southern Illinois | 6-21 |