| 09/04/05 | at | Kentucky | 31-24 |
| 09/17/05 | hosting | Oregon State | 63-27 |
| 09/24/05 | at | South Florida | 14-45 |
| 10/01/05 | hosting | Florida Atlantic | 61-10 |
| 10/08/05 | hosting | North Carolina | 69-14 |
| 10/15/05 | at | West Virginia | 44-46 3OT |
| 10/22/05 | at | Cincinnati | 46-22 |
| 11/03/05 | hosting | Pittsburgh | 42-20 |
| 11/11/05 | hosting | Rutgers | 56-5 |
| 11/26/05 | hosting | Syracuse | 41-17 |
| 12/03/05 | at | Connecticut | 30-20 |
| 01/02/06 | vs. | Virginia Tech | 0.399163762162816 |