| 09/10/05 | at | Mount Ida | 21-13 |
| 09/17/05 | hosting | Curry | 28-21 |
| 09/24/05 | at | Mass Maritime | 41-28 |
| 10/01/05 | hosting | Nichols | 38-13 |
| 10/08/05 | at | Bridgewater St MA | 24-33 |
| 10/15/05 | at | Fitchburg St | 0-21 |
| 10/22/05 | hosting | Worcester St | 35-7 |
| 10/29/05 | at | Westfield St | 21-11 |
| 11/05/05 | hosting | Framingham St | 35-6 |
| 11/19/05 | at | Alfred | 20-63 |