| 09/03/05 | hosting | Emory & Henry | 25-7 |
| 09/17/05 | at | Heidelberg | 46-21 |
| 09/24/05 | hosting | John Carroll | 17-48 |
| 10/01/05 | hosting | Otterbein | 17-31 |
| 10/08/05 | at | Capital | 10-41 |
| 10/15/05 | hosting | Mount Union | 7-59 |
| 10/22/05 | hosting | Muskingum | 18-17 |
| 10/29/05 | at | Wilmington | 18-3 |
| 11/05/05 | at | Baldwin-Wallace | 32-31 |
| 11/12/05 | hosting | Ohio Northern | 7-58 |