| 09/03/05 | hosting | Delaware Valley | 22-31 |
| 09/10/05 | hosting | Susquehanna | 22-10 |
| 09/17/05 | at | King's PA | 29-18 |
| 09/24/05 | hosting | Juniata | 49-14 |
| 10/01/05 | at | Widener | 24-34 |
| 10/15/05 | at | FDU-Florham | 41-17 |
| 10/22/05 | hosting | Wilkes | 17-27 |
| 10/29/05 | at | Lycoming | 13-17 |
| 11/05/05 | hosting | Lebanon Valley | 38-35 |
| 11/12/05 | at | Muhlenberg | 24-19 |
| 11/19/05 | at | Frostburg St | 14-7 |