| 09/03/05 | hosting | TCU | 10-17 |
| 09/10/05 | hosting | Tulsa | 31-15 |
| 09/17/05 | at | UCLA | 24-41 |
| 10/01/05 | hosting | Kansas St | 43-21 |
| 10/08/05 | vs. | Texas | 12-45 |
| 10/15/05 | vs. | Kansas | 19-3 |
| 10/22/05 | hosting | Baylor | 37-30 2OT |
| 10/29/05 | at | Nebraska | 31-24 |
| 11/12/05 | hosting | Texas A&M | 36-30 |
| 11/19/05 | at | Texas Tech | 21-23 |
| 11/26/05 | hosting | Oklahoma State | 42-14 |
| 12/29/05 | vs. | Oregon | 0.45847502637439874 |