| 08/27/05 | at | Northwood | 9-7 |
| 09/10/05 | hosting | Wayne St MI | 29-3 |
| 09/17/05 | hosting | Findlay | 42-3 |
| 09/24/05 | at | Hillsdale | 24-3 |
| 10/01/05 | at | Indianapolis | 27-7 |
| 10/08/05 | hosting | Mercyhurst | 44-14 |
| 10/15/05 | at | Grand Valley St | 10-31 |
| 10/22/05 | at | Northern Michigan | 31-20 |
| 10/29/05 | hosting | Michigan Tech | 17-10 |
| 11/05/05 | hosting | Ferris St | 39-32 |
| 11/12/05 | hosting | Northwood | 31-16 |
| 11/19/05 | at | Nebraska-Omaha | 24-21 |
| 11/26/05 | at | Grand Valley St | 17-24 |