| 08/27/05 | vs. | Graceland | 20-24 |
| 09/01/05 | at | Angelo St | 7-42 |
| 09/10/05 | at | Panhandle St | 17-16 |
| 09/24/05 | hosting | Peru St | 46-7 |
| 10/01/05 | at | Haskell | 35-7 |
| 10/08/05 | hosting | NW Oklahoma St | 24-35 |
| 10/22/05 | hosting | Bacone | 17-10 |
| 10/29/05 | at | Langston | 35-19 |
| 11/05/05 | hosting | Texas College | 7-22 |
| 11/12/05 | hosting | SW Assem of God | 41-21 |