| 09/10/05 | hosting | Anderson | 14-52 |
| 09/17/05 | hosting | William Penn | 22-25 |
| 09/24/05 | at | St Ambrose | 7-56 |
| 10/01/05 | at | Quincy | 19-26 |
| 10/08/05 | hosting | Urbana | 17-30 |
| 10/15/05 | hosting | Walsh | 14-45 |
| 10/22/05 | at | St Francis IN | 0-55 |
| 10/29/05 | hosting | Geneva | 0-42 |
| 11/05/05 | at | Malone | 32-34 |
| 11/12/05 | at | Ohio Dominican | 34-42 |