| 09/03/05 | at | Wisconsin Lutheran | 17-3 |
| 09/10/05 | at | South Dakota St | 6-69 |
| 09/17/05 | hosting | Morehead St | 7-48 |
| 09/24/05 | hosting | Davidson | 17-48 |
| 10/01/05 | at | Austin Peay | 20-30 |
| 10/08/05 | hosting | St Joseph's | 21-34 |
| 10/15/05 | at | Butler | 34-21 |
| 10/22/05 | at | Dayton | 7-52 |
| 10/29/05 | hosting | San Diego | 21-63 |
| 11/05/05 | hosting | Drake | 24-49 |
| 11/12/05 | at | Aurora | 13-7 |