| 09/03/05 | hosting | Davidson | 33-0 |
| 09/10/05 | hosting | William & Mary | 7-41 |
| 09/17/05 | at | Duke | 14-40 |
| 09/24/05 | hosting | Lehigh | 26-28 |
| 10/01/05 | at | Liberty | 10-7 |
| 10/08/05 | hosting | Charleston Southern | 34-12 |
| 10/15/05 | at | Wofford | 23-38 |
| 10/22/05 | hosting | Gardner-Webb | 52-55 |
| 10/29/05 | at | Coastal Carolina | 14-38 |
| 11/05/05 | at | Richmond | 3-38 |
| 11/19/05 | hosting | The Citadel | 14-22 |