| 09/04/05 | at | Syracuse | 15-7 |
| 09/10/05 | hosting | Wofford | 35-7 |
| 09/17/05 | at | Maryland | 31-19 |
| 09/24/05 | hosting | East Carolina | 20-15 |
| 10/01/05 | hosting | Virginia Tech | 17-34 |
| 10/08/05 | at | Rutgers | 27-14 |
| 10/15/05 | hosting | Louisville | 46-44 3OT |
| 11/02/05 | hosting | Connecticut | 45-13 |
| 11/09/05 | at | Cincinnati | 38-0 |
| 11/24/05 | hosting | Pittsburgh | 45-13 |
| 12/03/05 | at | South Florida | 28-13 |
| 01/02/06 | vs. | Georgia | 0.43106764382958696 |