| 09/10/05 | at | Wilkes | 0-13 |
| 09/17/05 | hosting | Lycoming | 15-7 |
| 09/24/05 | at | Lebanon Valley | 41-38 |
| 10/01/05 | hosting | Moravian | 34-24 |
| 10/08/05 | at | Albright | 33-19 |
| 10/15/05 | hosting | Susquehanna | 42-7 |
| 10/22/05 | at | King's PA | 24-31 |
| 10/29/05 | hosting | Juniata | 52-7 |
| 11/05/05 | at | Salisbury | 31-28 |
| 11/12/05 | at | Delaware Valley | 21-36 |
| 11/19/05 | hosting | Montclair St | 27-18 |