| 08/27/05 | hosting | Catawba | 10-20 |
| 09/03/05 | at | Howard | 6-20 |
| 09/10/05 | at | South Carolina St | 12-52 |
| 09/17/05 | hosting | Elizabeth City St | 24-23 |
| 09/24/05 | at | Virginia Union | 31-0 |
| 10/01/05 | at | Fayetteville St | 26-24 |
| 10/08/05 | at | Livingstone | 42-14 |
| 10/15/05 | hosting | North Carolina Central | 17-20 |
| 10/22/05 | hosting | Johnson C. Smith | 28-9 |
| 10/29/05 | hosting | St Augustine's | 35-33 |