| 09/02/06 | hosting | Wittenberg | 57-7 |
| 09/16/06 | hosting | Wilmington | 43-0 |
| 09/23/06 | at | Heidelberg | 65-7 |
| 09/30/06 | hosting | Marietta | 52-10 |
| 10/07/06 | at | John Carroll | 24-21 |
| 10/14/06 | at | Ohio Northern | 17-10 |
| 10/21/06 | hosting | Otterbein | 26-0 |
| 10/28/06 | at | Mount Union | 12-38 |
| 11/04/06 | hosting | Muskingum | 52-14 |
| 11/11/06 | at | Baldwin-Wallace | 19-7 |
| 11/18/06 | hosting | Wittenberg | 32-14 |
| 11/25/06 | hosting | North Central | 41-13 |
| 12/02/06 | at | Mount Union | 14-17 |