| 09/02/06 | at | Cincinnati | 0-31 |
| 09/09/06 | hosting | Western Kentucky | 26-21 |
| 09/16/06 | at | Western Carolina | 17-20 |
| 09/21/06 | at | Tennessee Tech | 14-27 |
| 09/30/06 | hosting | Jacksonville St | 0-28 |
| 10/07/06 | at | Samford | 31-12 |
| 10/14/06 | hosting | Eastern Illinois | 21-28 |
| 10/21/06 | at | SE Missouri St | 27-21 |
| 11/04/06 | hosting | Murray St | 51-21 |
| 11/11/06 | at | Tennessee-Martin | 31-28 |
| 11/18/06 | hosting | Tennessee St | 20-3 |