| 09/02/06 | hosting | Vanderbilt | 27-7 |
| 09/09/06 | hosting | Central Michigan | 41-17 |
| 09/16/06 | at | Notre Dame | 47-21 |
| 09/23/06 | hosting | Wisconsin | 27-13 |
| 09/30/06 | at | Minnesota | 28-14 |
| 10/07/06 | hosting | Michigan St | 31-13 |
| 10/14/06 | at | Penn State | 17-10 |
| 10/21/06 | hosting | Iowa | 20-6 |
| 10/28/06 | hosting | Northwestern | 17-3 |
| 11/04/06 | hosting | Ball St | 34-26 |
| 11/11/06 | at | Indiana | 34-3 |
| 11/18/06 | at | Ohio State | 39-42 |
| 01/01/07 | at | Southern Cal | 18-32 |