| 09/02/06 | hosting | McNeese St | 41-10 |
| 09/09/06 | hosting | Florida Int'l | 21-20 |
| 09/16/06 | at | Central Florida | 24-17 |
| 09/23/06 | at | Kansas | 7-13 |
| 09/29/06 | hosting | Rutgers | 20-22 |
| 10/07/06 | hosting | Connecticut | 38-16 |
| 10/14/06 | at | North Carolina | 37-20 |
| 10/22/06 | at | Cincinnati | 6-23 |
| 11/04/06 | hosting | Pittsburgh | 22-12 |
| 11/11/06 | hosting | Syracuse | 27-10 |
| 11/18/06 | at | Louisville | 8-31 |
| 11/25/06 | at | West Virginia | 24-19 |
| 12/23/06 | hosting | East Carolina | 24-7 |