| 09/02/06 | at | Indiana | 20-39 |
| 09/09/06 | hosting | Toledo | 31-10 |
| 09/16/06 | at | Virginia | 17-10 |
| 09/23/06 | hosting | Temple | 41-7 |
| 10/07/06 | at | Ohio U. | 20-27 |
| 10/14/06 | hosting | Northern Illinois | 16-14 |
| 10/21/06 | at | Ball St | 41-27 |
| 10/28/06 | hosting | Eastern Michigan | 18-15 |
| 11/04/06 | hosting | Miami OH | 27-24 |
| 11/10/06 | at | Central Michigan | 7-31 |
| 11/18/06 | at | Florida St | 20-28 |
| 11/24/06 | at | Akron | 17-0 |
| 01/06/07 | hosting | Cincinnati | 24-27 |