| 11/21/05 | vs. | Kansas | 61-49 |
| 11/22/05 | vs. | Connecticut | 70-79 |
| 11/23/05 | vs. | Michigan St. | 71-74 OT |
| 11/27/05 | hosting | Virginia | 81-51 |
| 12/03/05 | at | Houston | 65-69 |
| 12/08/05 | hosting | Northern Arizona | 75-66 |
| 12/10/05 | hosting | St. Mary's | 73-61 |
| 12/17/05 | at | Utah | 73-43 |
| 12/19/05 | hosting | Sam Houston St. | 87-51 |
| 12/21/05 | hosting | Western Kentucky | 86-81 OT |
| 12/29/05 | vs. | Washington St. | 70-52 |
| 12/31/05 | at | Washington | 96-95 2OT |
| 01/05/06 | hosting | UCLA | 79-85 |
| 01/07/06 | hosting | Southern California | 74-63 |
| 01/12/06 | at | Oregon St. | 65-75 |
| 01/14/06 | at | Oregon | 68-73 |
| 01/19/06 | hosting | Stanford | 90-81 OT |
| 01/21/06 | hosting | California | 60-55 |
| 01/25/06 | at | Arizona St. | 80-70 |
| 01/28/06 | at | North Carolina | 69-86 |
| 02/02/06 | at | Southern California | 70-77 |
| 02/04/06 | at | UCLA | 73-84 |
| 02/09/06 | hosting | Oregon | 70-68 |
| 02/11/06 | hosting | Oregon St. | 80-58 |
| 02/16/06 | at | California | 66-75 |
| 02/19/06 | at | Stanford | 76-72 |
| 02/25/06 | hosting | Arizona St. | 68-47 |
| 03/02/06 | hosting | Washington St. | 66-61 |
| 03/04/06 | hosting | Washington | 67-70 |
| 03/09/06 | vs. | Stanford | 73-68 |
| 03/10/06 | vs. | UCLA | 59-71 |
| 03/17/06 | vs. | Wisconsin | 94-75 |
| 03/19/06 | vs. | Villanova | 78-82 |