| 11/18/05 | hosting | NC Wilmington | 73-54 |
| 11/21/05 | at | Colorado St. | 82-83 |
| 11/26/05 | vs. | St. Mary's | 73-54 |
| 11/29/05 | at | Pennsylvania | 78-60 |
| 12/03/05 | hosting | Cal Poly | 93-75 |
| 12/07/05 | hosting | Utah | 76-52 |
| 12/17/05 | hosting | UC Irvine | 96-80 |
| 12/20/05 | at | Texas Christian | 77-59 |
| 12/22/05 | hosting | Mercer | 117-74 |
| 12/31/05 | hosting | Dartmouth | 83-65 |
| 01/03/06 | hosting | Savannah St. | 116-52 |
| 01/07/06 | at | Texas | 64-89 |
| 01/11/06 | hosting | Kansas | 63-75 |
| 01/14/06 | at | Missouri | 74-71 |
| 01/18/06 | hosting | Baylor | 81-48 |
| 01/21/06 | at | Oklahoma St. | 80-78 OT |
| 01/25/06 | hosting | Nebraska | 81-59 |
| 01/28/06 | hosting | Kansas St. | 79-75 |
| 02/05/06 | at | Iowa St. | 79-96 |
| 02/08/06 | at | Texas A&M | 58-61 |
| 02/11/06 | hosting | Texas Tech | 66-64 |
| 02/15/06 | hosting | Oklahoma | 84-75 |
| 02/18/06 | at | Kansas St. | 60-72 |
| 02/22/06 | at | Nebraska | 77-93 |
| 02/25/06 | hosting | Missouri | 78-60 |
| 03/01/06 | at | Kansas | 54-75 |
| 03/04/06 | hosting | Iowa St. | 84-82 |
| 03/09/06 | vs. | Baylor | 65-61 |
| 03/10/06 | vs. | Texas A&M | 53-86 |
| 03/15/06 | hosting | Old Dominion | 61-79 |