| 11/23/05 | hosting | Kennesaw St. | 87-42 |
| 11/26/05 | hosting | Norfolk St. | 80-69 |
| 11/30/05 | hosting | St. Francis PA | 85-68 |
| 12/02/05 | hosting | Boston University | 75-62 |
| 12/05/05 | vs. | Maryland | 78-70 |
| 12/08/05 | hosting | Florida International | 70-45 |
| 12/10/05 | at | Morgan St. | 102-75 |
| 12/17/05 | hosting | Maryland Eastern Shore | 98-72 |
| 12/30/05 | at | North Carolina St. | 58-79 |
| 01/04/06 | at | Temple | 72-60 |
| 01/07/06 | at | Marshall | 79-73 OT |
| 01/11/06 | hosting | St. Louis | 69-64 OT |
| 01/14/06 | hosting | Saint Joseph's | 82-70 |
| 01/16/06 | hosting | Stony Brook | 88-60 |
| 01/21/06 | at | Charlotte | 83-69 |
| 01/25/06 | at | Duquesne | 94-78 |
| 01/28/06 | hosting | Rhode Island | 81-62 |
| 02/02/06 | at | Xavier | 89-85 |
| 02/05/06 | hosting | Richmond | 80-55 |
| 02/08/06 | hosting | Dayton | 81-67 |
| 02/11/06 | at | Saint Joseph's | 64-62 |
| 02/15/06 | hosting | Massachusetts | 69-66 |
| 02/18/06 | at | Richmond | 64-51 |
| 02/22/06 | hosting | La Salle | 77-65 |
| 02/25/06 | at | Fordham | 78-67 |
| 03/01/06 | at | St. Bonaventure | 89-78 |
| 03/04/06 | hosting | Charlotte | 86-85 OT |
| 03/09/06 | vs. | Temple | 53-68 |
| 03/16/06 | vs. | NC Wilmington | 88-85 OT |
| 03/18/06 | vs. | Duke | 61-74 |