| 11/18/05 | hosting | Idaho | 69-60 |
| 11/21/05 | vs. | Maryland | 88-76 |
| 11/22/05 | vs. | Michigan St. | 109-106 3OT |
| 11/23/05 | vs. | Connecticut | 63-65 |
| 11/30/05 | hosting | Portland St. | 89-80 |
| 12/04/05 | at | Washington | 95-99 |
| 12/08/05 | hosting | Washington St. | 67-53 |
| 12/10/05 | vs. | Oklahoma St. | 64-62 |
| 12/17/05 | hosting | Virginia | 80-69 |
| 12/19/05 | hosting | Eastern Washington | 75-65 |
| 12/22/05 | at | St. Louis | 60-57 |
| 12/27/05 | at | Memphis | 72-83 |
| 12/31/05 | hosting | Saint Joseph's | 102-94 |
| 01/07/06 | at | St. Mary's | 68-60 |
| 01/09/06 | at | Santa Clara | 81-68 |
| 01/14/06 | hosting | Pepperdine | 102-73 |
| 01/16/06 | hosting | Loyola Marymount | 92-80 |
| 01/21/06 | at | San Diego | 64-63 |
| 01/23/06 | at | San Francisco | 84-75 |
| 01/28/06 | hosting | Portland | 81-64 |
| 02/04/06 | hosting | Santa Clara | 85-71 |
| 02/06/06 | hosting | St. Mary's | 62-61 |
| 02/11/06 | hosting | Stanford | 80-76 |
| 02/13/06 | at | Portland | 97-83 |
| 02/18/06 | at | Loyola Marymount | 79-70 |
| 02/20/06 | at | Pepperdine | 81-71 |
| 02/25/06 | hosting | San Diego | 75-59 |
| 02/27/06 | hosting | San Francisco | 75-72 |
| 03/05/06 | hosting | San Diego | 96-92 OT |
| 03/06/06 | hosting | Loyola Marymount | 68-67 |
| 03/16/06 | vs. | Xavier | 79-75 |
| 03/18/06 | vs. | Indiana | 90-80 |
| 03/23/06 | vs. | UCLA | 71-73 |