| 11/18/05 | hosting | Georgia Southern | 83-58 |
| 11/23/05 | hosting | New Mexico | 68-56 |
| 11/26/05 | hosting | Stephen F. Austin | 71-54 |
| 11/30/05 | hosting | Cal St. Fullerton | 84-59 |
| 12/03/05 | at | Washington St. | 57-58 |
| 12/05/05 | hosting | Longwood | 89-60 |
| 12/07/05 | hosting | Colorado St. | 71-67 |
| 12/17/05 | hosting | Bethune Cookman | 74-61 |
| 12/20/05 | at | Northern Illinois | 70-75 OT |
| 12/29/05 | hosting | Belmont | 66-62 |
| 01/02/06 | hosting | North Dakota St. | 82-56 |
| 01/07/06 | at | Iowa St. | 70-72 |
| 01/11/06 | hosting | Nebraska | 42-57 |
| 01/14/06 | at | Kansas | 59-55 |
| 01/18/06 | hosting | Texas A&M | 58-54 |
| 01/21/06 | hosting | Missouri | 79-64 |
| 01/28/06 | at | Colorado | 75-79 |
| 02/01/06 | at | Baylor | 70-72 OT |
| 02/04/06 | hosting | Oklahoma St. | 61-63 |
| 02/08/06 | hosting | Iowa St. | 66-63 |
| 02/12/06 | at | Missouri | 71-74 |
| 02/15/06 | at | Texas Tech | 56-70 |
| 02/18/06 | hosting | Colorado | 72-60 |
| 02/22/06 | hosting | Texas | 64-65 |
| 02/25/06 | at | Oklahoma | 70-71 |
| 03/01/06 | at | Nebraska | 66-64 |
| 03/04/06 | hosting | Kansas | 52-66 |
| 03/09/06 | vs. | Texas Tech | 65-73 |