| 11/15/05 | hosting | Wisconsin Milwaukee | 79-52 |
| 11/17/05 | at | Alabama | 87-76 |
| 11/23/05 | vs. | UCLA | 88-80 |
| 11/25/05 | vs. | Duke | 67-70 |
| 11/28/05 | hosting | Lamar | 108-83 |
| 11/30/05 | hosting | Jackson St. | 97-70 |
| 12/03/05 | at | Cincinnati | 91-81 |
| 12/10/05 | at | Providence | 97-89 |
| 12/17/05 | at | Mississippi | 72-49 |
| 12/20/05 | hosting | Louisiana Tech | 76-58 |
| 12/27/05 | hosting | Gonzaga | 83-72 |
| 12/30/05 | hosting | Purdue | 90-70 |
| 01/02/06 | hosting | Texas | 58-69 |
| 01/04/06 | hosting | Middle Tennessee | 83-50 |
| 01/08/06 | hosting | Winthrop | 73-63 |
| 01/11/06 | at | East Carolina | 77-67 |
| 01/14/06 | hosting | Southern Methodist | 73-53 |
| 01/18/06 | hosting | Tennessee | 88-79 |
| 01/21/06 | at | Southern Mississippi | 85-68 |
| 01/26/06 | hosting | UAB | 73-66 |
| 01/28/06 | hosting | Central Florida | 94-61 |
| 02/01/06 | at | Tulsa | 84-61 |
| 02/04/06 | at | Rice | 84-79 |
| 02/11/06 | at | Marshall | 91-81 |
| 02/14/06 | hosting | Southern Mississippi | 80-41 |
| 02/18/06 | at | Tulane | 105-65 |
| 02/22/06 | hosting | Texas El Paso | 66-56 |
| 02/25/06 | hosting | Tulsa | 78-67 |
| 03/02/06 | at | UAB | 74-80 |
| 03/04/06 | hosting | Houston | 69-62 |
| 03/09/06 | hosting | Tulane | 75-56 |
| 03/10/06 | hosting | Houston | 68-54 |
| 03/11/06 | hosting | UAB | 57-46 |
| 03/17/06 | vs. | Oral Roberts | 94-78 |
| 03/19/06 | vs. | Bucknell | 72-56 |
| 03/23/06 | vs. | Bradley | 80-64 |
| 03/25/06 | vs. | UCLA | 45-50 |