| 11/19/05 | hosting | Gardner Webb | 83-80 |
| 11/22/05 | hosting | Cleveland St. | 112-55 |
| 11/25/05 | hosting | UC Santa Barbara | 83-66 |
| 11/29/05 | hosting | Illinois | 64-68 |
| 12/03/05 | at | Kentucky | 83-79 |
| 12/07/05 | hosting | St. Louis | 75-63 |
| 12/17/05 | hosting | Santa Clara | 76-58 |
| 12/21/05 | at | Southern California | 59-74 |
| 12/28/05 | hosting | NC Asheville | 89-47 |
| 01/03/06 | hosting | Davidson | 82-58 |
| 01/07/06 | hosting | North Carolina St. | 82-69 |
| 01/10/06 | at | Virginia Tech | 64-61 |
| 01/14/06 | hosting | Miami FL | 70-81 |
| 01/19/06 | at | Virginia | 68-72 |
| 01/22/06 | at | Florida St. | 81-80 |
| 01/25/06 | hosting | Boston College | 74-81 |
| 01/28/06 | hosting | Arizona | 86-69 |
| 02/02/06 | at | Maryland | 77-62 |
| 02/04/06 | hosting | Clemson | 76-61 |
| 02/07/06 | hosting | Duke | 83-87 |
| 02/12/06 | at | Miami FL | 80-70 |
| 02/15/06 | hosting | Georgia Tech | 82-75 |
| 02/19/06 | at | Wake Forest | 83-72 |
| 02/22/06 | at | North Carolina St. | 95-71 |
| 02/26/06 | hosting | Maryland | 81-57 |
| 03/01/06 | hosting | Virginia | 99-54 |
| 03/04/06 | at | Duke | 83-76 |
| 03/10/06 | vs. | Virginia | 79-67 |
| 03/11/06 | vs. | Boston College | 82-85 |
| 03/17/06 | vs. | Murray St. | 69-65 |
| 03/19/06 | vs. | George Mason | 60-65 |