| 11/20/05 | vs. | Western Carolina | 68-46 |
| 11/23/05 | at | Western Michigan | 69-63 |
| 11/27/05 | hosting | Upper Iowa | 72-47 |
| 11/29/05 | at | Iowa St. | 61-68 |
| 12/03/05 | hosting | Loyola Chicago | 72-56 |
| 12/06/05 | hosting | Iowa | 67-63 OT |
| 12/10/05 | hosting | Missouri Kansas City | 87-64 |
| 12/17/05 | hosting | Florida A&M | 76-53 |
| 12/19/05 | at | Louisiana St. | 54-50 |
| 12/22/05 | vs. | Hawaii Pacific | 81-47 |
| 12/23/05 | vs. | Dayton | 74-67 |
| 12/28/05 | at | Bradley | 60-68 OT |
| 12/31/05 | hosting | Evansville | 71-60 |
| 01/02/06 | hosting | Illinois St. | 60-47 |
| 01/05/06 | at | Wichita St. | 75-61 |
| 01/07/06 | at | Missouri St. | 72-62 |
| 01/11/06 | hosting | Creighton | 52-55 |
| 01/14/06 | at | Illinois St. | 67-52 |
| 01/16/06 | hosting | Southern Illinois | 71-65 2OT |
| 01/21/06 | hosting | Drake | 91-72 |
| 01/25/06 | at | Evansville | 74-61 |
| 01/28/06 | at | Drake | 51-49 |
| 01/31/06 | at | Creighton | 55-63 |
| 02/04/06 | hosting | Indiana St. | 83-56 |
| 02/07/06 | hosting | Wichita St. | 68-56 |
| 02/11/06 | hosting | Missouri St. | 63-66 |
| 02/14/06 | at | Indiana St. | 60-61 |
| 02/18/06 | hosting | Bucknell | 65-61 2OT |
| 02/22/06 | hosting | Bradley | 49-71 |
| 02/25/06 | at | Southern Illinois | 45-46 |
| 03/03/06 | vs. | Missouri St. | 57-42 |
| 03/04/06 | vs. | Southern Illinois | 46-55 OT |
| 03/17/06 | vs. | Georgetown | 49-54 |