| (55.74) | ||||
| 11/14/09 | hosting | North Carolina Central | (40.86) | 83-53 |
| 11/16/09 | hosting | Nova Southeastern | (41.46) | 108-58 |
| 11/19/09 | vs. | Tulane | (46.80) | 74-54 |
| 11/20/09 | vs. | NC Wilmington | (47.06) | 67-60 |
| 11/22/09 | vs. | South Carolina | (53.70) | 85-70 |
| 11/25/09 | hosting | Florida Gulf Coast | (43.71) | 77-58 |
| 11/28/09 | hosting | South Carolina Upstate | (44.67) | 70-41 |
| 12/02/09 | hosting | Minnesota | (57.41) | 63-58 |
| 12/06/09 | at | Boston College | (54.14) | 60-61 |
| 12/12/09 | hosting | South Carolina St. | (45.87) | 91-54 |
| 12/16/09 | at | Stetson | (41.45) | 69-49 |
| 12/19/09 | vs. | Florida Atlantic | (48.38) | 87-69 |
| 12/21/09 | hosting | North Carolina A&T | (43.03) | 80-59 |
| 12/30/09 | hosting | Bethune Cookman | (44.58) | 73-55 |
| 01/03/10 | at | Pepperdine | (43.91) | 86-63 |
| 01/09/10 | hosting | Wake Forest | (55.03) | 67-66 |
| 01/13/10 | at | Virginia Tech | (56.25) | 66-81 |
| 01/16/10 | at | Virginia | (54.07) | 57-75 |
| 01/19/10 | hosting | Boston College | (54.14) | 75-79 |
| 01/26/10 | at | Maryland | (59.61) | 59-81 |
| 01/31/10 | hosting | Virginia Tech | (56.25) | 82-75 |
| 02/02/10 | at | Wake Forest | (55.03) | 53-62 |
| 02/06/10 | at | Florida St. | (57.14) | 65-71 |
| 02/10/10 | hosting | Georgia Tech | (57.74) | 64-62 |
| 02/13/10 | at | Clemson | (58.07) | 66-74 |
| 02/17/10 | hosting | Duke | (64.08) | 74-81 |
| 02/23/10 | hosting | Virginia | (54.07) | 74-62 |
| 02/27/10 | hosting | North Carolina St. | (54.65) | 66-71 |
| 03/02/10 | at | North Carolina | (55.28) | 62-69 |
| 03/06/10 | hosting | Florida St. | (57.14) | 60-61 |
| 03/11/10 | vs. | Wake Forest | (55.03) | 83-62 |
| 03/12/10 | vs. | Virginia Tech | (56.25) | 70-65 |
| 03/13/10 | vs. | Duke | (64.08) | 74-77 |