| 10/07/05 | at | Colgate | 2-6 |
| 10/09/05 | hosting | Rensselaer | 5-3 |
| 10/15/05 | at | Boston University | 1-3 |
| 10/21/05 | at | Providence | 0-3 |
| 10/22/05 | hosting | Providence | 0-4 |
| 10/28/05 | hosting | Boston University | 7-4 |
| 10/29/05 | hosting | Union | 3-4 |
| 11/02/05 | at | Merrimack | 3-1 |
| 11/11/05 | hosting | Maine | 2-9 |
| 11/18/05 | at | New Hampshire | 2-3 |
| 11/19/05 | hosting | New Hampshire | 6-3 |
| 12/02/05 | at | St. Lawrence | 2-4 |
| 12/03/05 | at | Vermont | 2-5 |
| 12/10/05 | at | New Hampshire | 1-4 |
| 12/11/05 | hosting | Dartmouth | 3-2 |
| 12/29/05 | vs. | Canisius | 5-4 |
| 12/30/05 | at | Minnesota | 4-5 |
| 01/06/06 | at | Maine | 0-4 |
| 01/07/06 | at | Maine | 2-6 |
| 01/13/06 | hosting | Massachusetts | 6-2 |
| 01/15/06 | at | Providence | 4-3 OT |
| 01/20/06 | at | Northeastern | 2-1 |
| 01/21/06 | hosting | Northeastern | 2-2 OT |
| 01/27/06 | at | Massachusetts | 3-2 |
| 01/28/06 | hosting | Boston College | 3-4 OT |
| 02/03/06 | hosting | Boston University | 1-5 |
| 02/04/06 | hosting | Massachusetts | 2-5 |
| 02/10/06 | at | Northeastern | 4-6 |
| 02/17/06 | at | Merrimack | 2-2 OT |
| 02/18/06 | hosting | Merrimack | 5-2 |
| 02/23/06 | at | Boston College | 0-6 |
| 02/25/06 | hosting | Boston College | 6-3 |
| 03/03/06 | hosting | Vermont | 3-2 |
| 03/04/06 | hosting | Vermont | 5-2 |
| 03/10/06 | at | Maine | 3-4 OT |
| 03/11/06 | at | Maine | 3-4 |