| 10/07/05 | hosting | Mercyhurst | 4-3 |
| 10/08/05 | hosting | Mercyhurst | 2-5 |
| 10/14/05 | vs. | Vermont | 3-4 OT |
| 10/15/05 | vs. | Rensselaer | 3-4 |
| 10/21/05 | at | Northern Michigan | 1-5 |
| 10/22/05 | hosting | Northern Michigan | 1-2 |
| 10/28/05 | hosting | Minnesota-Duluth | 3-6 |
| 10/29/05 | hosting | Minnesota-Duluth | 2-2 OT |
| 11/04/05 | at | Denver | 2-5 |
| 11/05/05 | at | Denver | 3-4 |
| 11/11/05 | hosting | St. Cloud State | 3-2 OT |
| 11/12/05 | hosting | St. Cloud State | 0-7 |
| 11/18/05 | at | Colorado College | 0-5 |
| 11/19/05 | at | Colorado College | 0-3 |
| 12/02/05 | hosting | North Dakota | 1-6 |
| 12/03/05 | hosting | North Dakota | 2-8 |
| 12/09/05 | at | Wisconsin | 4-2 |
| 12/10/05 | at | Wisconsin | 0-7 |
| 12/16/05 | hosting | Minnesota State | 4-5 |
| 12/17/05 | hosting | Minnesota State | 3-2 |
| 12/29/05 | vs. | Michigan State | 2-3 OT |
| 12/30/05 | vs. | Michigan | 3-5 |
| 01/13/06 | at | Minnesota-Duluth | 4-2 |
| 01/14/06 | at | Minnesota-Duluth | 3-1 |
| 01/20/06 | hosting | Alaska-Anchorage | 2-2 OT |
| 01/21/06 | hosting | Alaska-Anchorage | 2-2 OT |
| 02/03/06 | at | Minnesota State | 0-4 |
| 02/04/06 | at | Minnesota State | 3-2 |
| 02/10/06 | hosting | Minnesota | 4-7 |
| 02/11/06 | hosting | Minnesota | 2-2 OT |
| 02/17/06 | hosting | Wisconsin | 0-5 |
| 02/18/06 | hosting | Wisconsin | 4-4 OT |
| 02/24/06 | at | St. Cloud State | 1-6 |
| 02/25/06 | at | St. Cloud State | 2-2 OT |
| 03/03/06 | at | North Dakota | 0-4 |
| 03/04/06 | at | North Dakota | 0-6 |
| 03/10/06 | at | Wisconsin | 1-4 |
| 03/11/06 | at | Wisconsin | 0-1 |