| 10/14/05 | hosting | Army | 3-2 |
| 10/15/05 | hosting | New Hampshire | 5-3 |
| 10/21/05 | hosting | Miami | 3-6 |
| 10/22/05 | hosting | Miami | 2-3 |
| 11/04/05 | at | Bowling Green | 3-7 |
| 11/05/05 | at | Bowling Green | 3-4 |
| 11/11/05 | at | Michigan State | 7-4 |
| 11/12/05 | at | Michigan State | 3-2 OT |
| 11/18/05 | hosting | Alaska-Fairbanks | 4-2 |
| 11/19/05 | hosting | Alaska-Fairbanks | 3-4 |
| 11/22/05 | hosting | Minnesota State | 3-6 |
| 11/25/05 | vs. | Providence | 4-2 |
| 11/26/05 | vs. | Holy Cross | 6-1 |
| 12/02/05 | hosting | Ferris State | 5-2 |
| 12/04/05 | hosting | Ferris State | 5-3 |
| 12/09/05 | at | Michigan | 2-4 |
| 12/10/05 | at | Michigan | 3-7 |
| 12/29/05 | hosting | Alabama-Huntsville | 8-5 |
| 12/31/05 | hosting | Yale | 3-2 OT |
| 01/03/06 | at | Minnesota State | 2-5 |
| 01/06/06 | hosting | Notre Dame | 1-4 |
| 01/07/06 | hosting | Notre Dame | 2-2 OT |
| 01/13/06 | at | Ohio State | 2-0 |
| 01/14/06 | at | Ohio State | 2-2 OT |
| 01/20/06 | hosting | Michigan State | 3-4 OT |
| 01/21/06 | hosting | Michigan State | 3-2 |
| 01/27/06 | at | Alaska-Fairbanks | 4-1 |
| 01/28/06 | at | Alaska-Fairbanks | 3-3 OT |
| 02/03/06 | hosting | Lake Superior | 8-0 |
| 02/04/06 | hosting | Lake Superior | 2-2 OT |
| 02/10/06 | at | Northern Michigan | 2-1 |
| 02/11/06 | at | Northern Michigan | 8-3 |
| 02/17/06 | hosting | Michigan | 4-3 |
| 02/18/06 | hosting | Michigan | 4-4 OT |
| 02/24/06 | at | Western Michigan | 5-5 OT |
| 02/25/06 | at | Western Michigan | 3-6 |
| 03/03/06 | hosting | Bowling Green | 4-2 |
| 03/04/06 | hosting | Bowling Green | 4-2 |
| 03/10/06 | at | Northern Michigan | 1-4 |
| 03/11/06 | at | Northern Michigan | 2-3 |
| 03/24/06 | vs. | Boston University | 2-9 |