| 10/14/05 | hosting | St. Cloud State | 3-0 |
| 10/15/05 | hosting | St. Cloud State | 2-3 OT |
| 10/21/05 | hosting | Michigan Tech | 5-1 |
| 10/22/05 | at | Michigan Tech | 2-1 |
| 10/28/05 | hosting | Lake Superior | 3-1 |
| 10/29/05 | at | Lake Superior | 2-1 |
| 11/04/05 | at | Michigan State | 4-5 OT |
| 11/05/05 | at | Michigan State | 0-5 |
| 11/11/05 | hosting | Michigan | 1-3 |
| 11/12/05 | hosting | Michigan | 3-4 OT |
| 11/18/05 | at | Bowling Green | 6-3 |
| 11/19/05 | at | Bowling Green | 4-8 |
| 11/25/05 | at | Alaska-Fairbanks | 1-3 |
| 11/26/05 | at | Alaska-Fairbanks | 4-1 |
| 12/09/05 | at | Ferris State | 3-5 |
| 12/10/05 | at | Ferris State | 2-1 |
| 12/17/05 | hosting | Western Michigan | 0-0 OT |
| 12/18/05 | hosting | Western Michigan | 5-2 |
| 12/30/05 | vs. | Wayne State | 6-2 |
| 12/31/05 | at | Wisconsin | 1-5 |
| 01/06/06 | at | Miami | 2-1 |
| 01/07/06 | at | Miami | 3-6 |
| 01/13/06 | hosting | Ferris State | 5-0 |
| 01/14/06 | hosting | Ferris State | 2-1 |
| 01/20/06 | hosting | Notre Dame | 5-2 |
| 01/21/06 | hosting | Notre Dame | 3-4 |
| 01/27/06 | at | Western Michigan | 2-4 |
| 01/28/06 | at | Western Michigan | 2-2 OT |
| 02/03/06 | hosting | Wayne State | 3-1 |
| 02/04/06 | hosting | Wayne State | 2-1 |
| 02/10/06 | hosting | Nebraska-Omaha | 1-2 |
| 02/11/06 | hosting | Nebraska-Omaha | 3-8 |
| 02/17/06 | at | Lake Superior | 4-3 OT |
| 02/18/06 | hosting | Lake Superior | 5-1 |
| 02/24/06 | hosting | Ohio State | 4-1 |
| 02/25/06 | hosting | Ohio State | 4-2 |
| 03/10/06 | hosting | Nebraska-Omaha | 4-1 |
| 03/11/06 | hosting | Nebraska-Omaha | 3-2 |
| 03/17/06 | vs. | Miami | 2-5 |
| 03/18/06 | vs. | Michigan | 2-3 |