| 10/21/05 | at | Colorado College | 1-3 |
| 10/22/05 | at | Denver | 3-6 |
| 10/28/05 | hosting | Princeton | 3-5 |
| 10/29/05 | hosting | Princeton | 2-0 |
| 11/04/05 | hosting | Michigan | 5-8 |
| 11/05/05 | at | Michigan | 2-4 |
| 11/10/05 | hosting | Bowling Green | 9-4 |
| 11/11/05 | hosting | Bowling Green | 4-2 |
| 11/18/05 | at | Miami | 2-2 OT |
| 11/19/05 | at | Miami | 0-3 |
| 11/25/05 | hosting | Ohio State | 1-4 |
| 11/26/05 | hosting | Ohio State | 2-5 |
| 12/02/05 | at | Western Michigan | 3-4 |
| 12/03/05 | hosting | Western Michigan | 3-0 |
| 12/06/05 | at | Minnesota State | 3-2 |
| 12/10/05 | hosting | Minnesota State | 1-2 |
| 12/17/05 | hosting | Lake Superior | 0-4 |
| 12/18/05 | hosting | Lake Superior | 4-3 |
| 01/06/06 | at | Nebraska-Omaha | 4-1 |
| 01/07/06 | at | Nebraska-Omaha | 2-2 OT |
| 01/13/06 | hosting | Miami | 2-2 OT |
| 01/14/06 | hosting | Miami | 2-3 |
| 01/20/06 | at | Northern Michigan | 2-5 |
| 01/21/06 | at | Northern Michigan | 4-3 |
| 01/27/06 | at | Ohio State | 0-1 |
| 01/28/06 | at | Ohio State | 1-0 |
| 02/03/06 | hosting | Michigan State | 2-3 |
| 02/04/06 | at | Michigan State | 1-2 |
| 02/10/06 | hosting | Ferris State | 4-1 |
| 02/11/06 | at | Ferris State | 3-2 |
| 02/17/06 | at | Bowling Green | 7-4 |
| 02/18/06 | at | Bowling Green | 1-1 OT |
| 02/24/06 | hosting | Alaska-Fairbanks | 4-1 |
| 02/25/06 | hosting | Alaska-Fairbanks | 1-2 |
| 03/03/06 | hosting | Alaska-Fairbanks | 1-3 |
| 03/04/06 | hosting | Alaska-Fairbanks | 0-1 |