| 10/08/05 | vs. | Michigan State | 1-5 |
| 10/09/05 | vs. | Miami | 0-4 |
| 10/28/05 | at | Clarkson | 2-5 |
| 10/29/05 | at | Clarkson | 1-7 |
| 11/04/05 | at | Niagara | 4-5 OT |
| 11/05/05 | at | Niagara | 3-3 OT |
| 11/11/05 | hosting | Bemidji State | 1-4 |
| 11/12/05 | hosting | Bemidji State | 1-3 |
| 11/25/05 | at | Union | 2-2 OT |
| 11/26/05 | at | Union | 0-4 |
| 12/02/05 | at | Air Force | 4-3 |
| 12/03/05 | at | Air Force | 6-7 |
| 12/09/05 | hosting | Merrimack | 3-2 |
| 12/10/05 | hosting | Merrimack | 6-5 OT |
| 12/30/05 | vs. | Northern Michigan | 2-6 |
| 12/31/05 | vs. | Western Michigan | 6-3 |
| 01/06/06 | at | Michigan State | 1-3 |
| 01/07/06 | at | Michigan State | 1-5 |
| 01/13/06 | at | Bemidji State | 3-3 OT |
| 01/14/06 | at | Bemidji State | 2-6 |
| 01/20/06 | hosting | Robert Morris | 2-2 OT |
| 01/21/06 | hosting | Robert Morris | 6-3 |
| 01/27/06 | hosting | Alabama-Huntsville | 2-2 OT |
| 01/28/06 | hosting | Alabama-Huntsville | 2-6 |
| 02/03/06 | at | Northern Michigan | 1-3 |
| 02/04/06 | at | Northern Michigan | 1-2 |
| 02/10/06 | at | Robert Morris | 7-7 OT |
| 02/11/06 | at | Robert Morris | 4-5 |
| 02/17/06 | hosting | Niagara | 3-4 |
| 02/18/06 | hosting | Niagara | 3-2 |
| 02/24/06 | at | Alabama-Huntsville | 1-2 |
| 02/25/06 | at | Alabama-Huntsville | 1-6 |
| 03/03/06 | hosting | Air Force | 1-3 |
| 03/04/06 | hosting | Air Force | 3-5 |
| 03/10/06 | hosting | Alabama-Huntsville | 1-3 |