| (50.04) | ||||
| 03/29/08 | at | New England Revolution | (49.74) | 0-3 |
| 04/06/08 | hosting | FC Dallas | (50.07) | 3-3 |
| 04/12/08 | at | Kansas City Wizards | (49.85) | 0-0 |
| 04/19/08 | at | Los Angeles Galaxy | (49.92) | 2-2 |
| 04/26/08 | at | Columbus Crew | (50.41) | 0-1 |
| 05/03/08 | hosting | Chivas USA | (49.94) | 0-0 |
| 05/10/08 | hosting | Colorado Rapids | (49.96) | 2-1 |
| 05/17/08 | at | Chicago Fire | (50.13) | 2-1 |
| 05/22/08 | at | San Jose Earthquakes | (49.65) | 1-2 |
| 05/28/08 | at | FC Dallas | (50.07) | 2-2 |
| 05/31/08 | hosting | New York Red Bulls | (50.01) | 1-0 |
| 06/04/08 | at | D.C. United | (49.88) | 0-0 |
| 06/08/08 | hosting | Toronto FC | (49.96) | 3-1 |
| 06/12/08 | hosting | New England Revolution | (49.74) | 0-2 |
| 06/21/08 | at | Colorado Rapids | (49.96) | 0-0 |
| 06/26/08 | hosting | FC Dallas | (50.07) | 1-1 |
| 07/03/08 | at | Real Salt Lake | (49.95) | 0-0 |
| 07/23/08 | at | D.C. United | (49.88) | 2-0 |
| 08/02/08 | hosting | Columbus Crew | (50.41) | 2-0 |
| 08/16/08 | hosting | Real Salt Lake | (49.95) | 4-3 |
| 08/20/08 | hosting | Chivas USA | (49.94) | 4-0 |
| 08/24/08 | at | New York Red Bulls | (50.01) | 0-3 |
| 08/31/08 | hosting | Chicago Fire | (50.13) | 2-1 |
| 09/07/08 | hosting | Kansas City Wizards | (49.85) | 3-1 |
| 09/13/08 | at | San Jose Earthquakes | (49.65) | 1-1 |
| 09/27/08 | at | Toronto FC | (49.96) | 1-1 |
| 10/04/08 | at | Colorado Rapids | (49.96) | 3-1 |
| 10/12/08 | hosting | D.C. United | (49.88) | 0-0 |
| 10/15/08 | hosting | San Jose Earthquakes | (49.65) | 2-1 |
| 10/18/08 | hosting | Los Angeles Galaxy | (49.92) | 3-0 |
| 10/25/08 | at | Chivas USA | (49.94) | 1-1 |
| 11/01/08 | at | New York Red Bulls | (50.01) | 1-1 |
| 11/09/08 | hosting | New York Red Bulls | (50.01) | 0-3 |