| 11/02/05 | at | Toronto | 99-96 |
| 11/04/05 | at | New York | 86-75 |
| 11/05/05 | hosting | Orlando | 87-79 |
| 11/09/05 | hosting | L.A. Clippers | 97-102 |
| 11/11/05 | hosting | Seattle | 137-96 |
| 11/12/05 | hosting | San Antonio | 110-95 |
| 11/15/05 | at | Cleveland | 99-114 |
| 11/17/05 | at | Minnesota | 98-109 |
| 11/19/05 | at | New Jersey | 83-89 |
| 11/22/05 | hosting | Denver | 105-108 |
| 11/23/05 | at | Orlando | 83-91 |
| 11/25/05 | at | Detroit | 120-114 2OT |
| 11/26/05 | at | Charlotte | 82-100 |
| 11/30/05 | hosting | Portland | 96-89 |
| 12/02/05 | hosting | Milwaukee | 102-105 |
| 12/06/05 | hosting | Toronto | 119-111 OT |
| 12/08/05 | at | Indiana | 87-111 |
| 12/10/05 | hosting | Chicago | 111-118 |
| 12/11/05 | at | Miami | 101-104 OT |
| 12/13/05 | hosting | New Jersey | 94-74 |
| 12/16/05 | at | L.A. Lakers | 91-97 |
| 12/18/05 | at | Portland | 92-97 |
| 12/19/05 | at | Seattle | 101-111 |
| 12/21/05 | at | Denver | 116-110 |
| 12/23/05 | at | Phoenix | 112-111 |
| 12/26/05 | hosting | L.A. Lakers | 94-91 |
| 12/28/05 | hosting | Phoenix | 99-104 |
| 12/30/05 | hosting | Miami | 113-128 |
| 01/03/06 | hosting | Houston | 111-123 |
| 01/06/06 | at | New York | 92-113 |
| 01/07/06 | hosting | Boston | 103-102 |
| 01/09/06 | hosting | Utah | 89-97 |
| 01/11/06 | hosting | Atlanta | 103-72 |
| 01/13/06 | at | Indiana | 94-85 |
| 01/14/06 | at | Atlanta | 114-106 OT |
| 01/16/06 | hosting | Philadelphia | 104-76 |
| 01/18/06 | at | Orlando | 98-106 |
| 01/20/06 | hosting | New Orleans/Okla Cty | 110-99 |
| 01/22/06 | hosting | Memphis | 82-93 |
| 01/25/06 | at | Boston | 89-87 |
| 01/27/06 | at | Chicago | 79-90 |
| 01/28/06 | hosting | Charlotte | 107-97 |
| 01/31/06 | hosting | Indiana | 84-79 |
| 02/01/06 | at | Toronto | 112-117 |
| 02/04/06 | hosting | Atlanta | 98-85 |
| 02/06/06 | hosting | Orlando | 94-82 |
| 02/08/06 | hosting | Golden State | 129-124 |
| 02/10/06 | hosting | Cleveland | 101-89 |
| 02/12/06 | hosting | Philadelphia | 107-97 |
| 02/13/06 | at | New Orleans/Okla Cty | 96-97 |
| 02/15/06 | at | Dallas | 97-103 |
| 02/21/06 | hosting | Minnesota | 90-78 |
| 02/24/06 | at | Cleveland | 102-94 |
| 02/25/06 | hosting | New York | 110-89 |
| 02/27/06 | at | Memphis | 98-108 |
| 03/01/06 | hosting | Indiana | 93-99 |
| 03/03/06 | at | Philadelphia | 113-119 |
| 03/05/06 | hosting | Sacramento | 117-107 |
| 03/07/06 | hosting | Boston | 115-116 OT |
| 03/08/06 | at | Miami | 112-118 |
| 03/11/06 | hosting | Detroit | 110-92 |
| 03/14/06 | at | Charlotte | 119-114 |
| 03/15/06 | hosting | Charlotte | 107-99 |
| 03/17/06 | hosting | Dallas | 94-104 |
| 03/19/06 | hosting | Chicago | 113-104 |
| 03/21/06 | hosting | New Jersey | 100-112 |
| 03/23/06 | at | Utah | 109-97 |
| 03/25/06 | at | L.A. Clippers | 101-116 |
| 03/27/06 | at | Golden State | 116-98 |
| 03/28/06 | at | Sacramento | 97-84 |
| 03/31/06 | at | Houston | 103-105 |
| 04/01/06 | at | San Antonio | 99-106 |
| 04/04/06 | hosting | New York | 105-90 |
| 04/05/06 | at | Boston | 108-91 |
| 04/07/06 | at | Atlanta | 101-114 |
| 04/08/06 | hosting | Miami | 86-99 |
| 04/10/06 | at | Philadelphia | 97-105 |
| 04/12/06 | at | Milwaukee | 97-100 |
| 04/14/06 | at | Chicago | 101-103 |
| 04/16/06 | hosting | Cleveland | 104-92 |
| 04/18/06 | hosting | Milwaukee | 116-103 |
| 04/19/06 | at | Detroit | 96-80 |
| 04/22/06 | at | Cleveland | 86-97 |
| 04/25/06 | at | Cleveland | 89-84 |
| 04/28/06 | hosting | Cleveland | 96-97 |
| 04/30/06 | hosting | Cleveland | 106-96 |
| 05/03/06 | at | Cleveland | 120-121 OT |
| 05/05/06 | hosting | Cleveland | 113-114 OT |