| 09/10/06 | at | Cleveland | 19-14 |
| 09/17/06 | at | Green Bay | 34-27 |
| 09/25/06 | hosting | Atlanta | 23-3 |
| 10/01/06 | at | Carolina | 18-21 |
| 10/08/06 | hosting | Tampa Bay | 24-21 |
| 10/15/06 | hosting | Philadelphia | 27-24 |
| 10/29/06 | hosting | Baltimore | 22-35 |
| 11/05/06 | at | Tampa Bay | 31-14 |
| 11/12/06 | at | Pittsburgh | 31-38 |
| 11/19/06 | hosting | Cincinnati | 16-31 |
| 11/26/06 | at | Atlanta | 31-13 |
| 12/03/06 | hosting | San Francisco | 34-10 |
| 12/10/06 | at | Dallas | 42-17 |
| 12/17/06 | hosting | Washington | 10-16 |
| 12/24/06 | at | N.Y. Giants | 30-7 |
| 12/31/06 | hosting | Carolina | 21-31 |
| 01/13/07 | hosting | Philadelphia | 27-24 |
| 01/21/07 | at | Chicago | 14-39 |