| (50.67) | ||||
| 09/07/08 | hosting | Carolina | (50.53) | 24-26 |
| 09/14/08 | at | Denver | (47.91) | 38-39 |
| 09/22/08 | hosting | N.Y. Jets | (49.11) | 48-29 |
| 09/28/08 | at | Oakland | (48.11) | 28-18 |
| 10/05/08 | at | Miami | (50.61) | 10-17 |
| 10/12/08 | hosting | New England | (52.17) | 30-10 |
| 10/19/08 | at | Buffalo | (48.24) | 14-23 |
| 10/26/08 | at | New Orleans | (49.90) | 32-37 |
| 11/09/08 | hosting | Kansas City | (46.16) | 20-19 |
| 11/16/08 | at | Pittsburgh | (53.51) | 10-11 |
| 11/23/08 | hosting | Indianapolis | (52.21) | 20-23 |
| 11/30/08 | hosting | Atlanta | (50.90) | 16-22 |
| 12/04/08 | hosting | Oakland | (48.11) | 34-7 |
| 12/14/08 | at | Kansas City | (46.16) | 22-21 |
| 12/21/08 | at | Tampa Bay | (48.97) | 41-24 |
| 12/28/08 | hosting | Denver | (47.91) | 52-21 |
| 01/03/09 | hosting | Indianapolis | (52.21) | 23-17 OT |
| 01/11/09 | at | Pittsburgh | (53.51) | 24-35 |