| 11/12/06 | hosting | Butler | 65-47 |
| 11/14/06 | at | Ill. Chicago | 53-48 |
| 11/18/06 | hosting | Loyola Chicago | 87-59 |
| 11/20/06 | at | Northern Illinois | 63-69 |
| 11/22/06 | hosting | Northern Colorado | 76-39 |
| 11/25/06 | hosting | St. Joseph's | 69-56 |
| 11/29/06 | at | Saint Louis | 84-75 |
| 12/02/06 | at | Mississippi | 50-75 |
| 12/05/06 | hosting | Florida | 80-57 |
| 12/09/06 | hosting | Rhode Island | 73-48 |
| 12/17/06 | hosting | IPFW | 74-47 |
| 12/21/06 | at | Bradley | 57-41 |
| 12/28/06 | hosting | Penn St. | 74-65 OT |
| 12/31/06 | at | Minnesota | 61-70 |
| 01/04/07 | at | Michigan | 70-51 |
| 01/07/07 | hosting | Indiana | 64-71 |
| 01/14/07 | at | Wisconsin | 70-62 |
| 01/18/07 | hosting | Minnesota | 64-54 |
| 01/21/07 | at | Ohio St. | 52-62 |
| 01/28/07 | hosting | Northwestern | 77-49 |
| 02/01/07 | hosting | Michigan | 65-44 |
| 02/04/07 | at | Michigan St. | 70-80 |
| 02/08/07 | at | Purdue | 57-69 |
| 02/11/07 | hosting | Ohio St. | 60-69 |
| 02/15/07 | at | Iowa | 74-69 |
| 02/18/07 | at | Indiana | 68-81 |
| 02/22/07 | hosting | Michigan St. | 56-46 |
| 02/25/07 | hosting | Purdue | 48-58 |
| 03/02/07 | vs. | Penn St. | 49-61 |
| 03/22/07 | at | Kansas St. | 51-66 |