| (45.94) | ||||
| 11/17/09 | hosting | Houston | (52.79) | 74-78 |
| 11/24/09 | hosting | Mo. Kansas City | (45.48) | 72-61 |
| 11/27/09 | hosting | Prairie View A&M | (47.55) | 58-65 |
| 11/28/09 | at | Texas Tech | (55.55) | 37-71 |
| 11/29/09 | hosting | San Francisco | (43.40) | 70-67 |
| 12/03/09 | at | Oklahoma | (62.15) | 67-100 |
| 12/12/09 | at | SE Missouri St. | (37.71) | 66-54 |
| 12/15/09 | at | Arkansas St. | (47.28) | 60-67 OT |
| 12/19/09 | at | St. John's | (61.90) | 47-79 |
| 12/20/09 | hosting | UAB | (50.87) | 46-59 |
| 12/30/09 | at | Houston Baptist | (34.47) | 77-65 |
| 01/05/10 | at | Texas | (60.95) | 41-84 |
| 01/09/10 | at | Texas St. | (42.24) | 66-60 |
| 01/13/10 | hosting | Lamar | (50.77) | 63-67 |
| 01/16/10 | at | UTSA | (46.93) | 51-69 |
| 01/20/10 | hosting | Stephen F. Austin | (48.65) | 85-79 |
| 01/23/10 | at | Sam Houston St. | (42.85) | 75-77 OT |
| 01/30/10 | hosting | Texas St. | (42.24) | 71-59 |
| 02/03/10 | at | TAMU Corpus Christi | (46.91) | 66-72 |
| 02/06/10 | at | Northwestern St. | (44.97) | 86-82 |
| 02/10/10 | hosting | McNeese St. | (39.66) | 77-65 |
| 02/13/10 | hosting | UTSA | (46.93) | 78-71 |
| 02/17/10 | at | SE Louisiana | (41.26) | 74-64 |
| 02/20/10 | hosting | Central Arkansas | (45.56) | 59-67 |
| 02/24/10 | at | Lamar | (50.77) | 73-79 |
| 02/27/10 | hosting | Sam Houston St. | (42.85) | 87-76 |
| 03/03/10 | at | Nicholls St. | (37.86) | 87-78 OT |
| 03/06/10 | hosting | TAMU Corpus Christi | (46.91) | 57-65 |
| 03/09/10 | at | UTSA | (46.93) | 68-63 |
| 03/11/10 | vs. | Lamar | (50.77) | 61-70 |