| (53.28) | ||||
| 11/16/09 | at | VCU | (55.02) | 58-72 |
| 11/19/09 | hosting | George Mason | (45.91) | 70-41 |
| 11/22/09 | at | James Madison | (57.05) | 59-66 |
| 11/25/09 | at | Radford | (43.18) | 78-51 |
| 11/28/09 | hosting | Elon | (43.72) | 82-46 |
| 12/03/09 | hosting | Michigan | (58.02) | 51-71 |
| 12/06/09 | hosting | N.C. Central | (42.39) | 85-44 |
| 12/09/09 | hosting | Mount St. Mary's | (44.14) | 44-42 |
| 12/19/09 | at | UAB | (50.87) | 68-66 OT |
| 12/20/09 | at | St. John's | (61.90) | 62-75 |
| 12/29/09 | hosting | N.J.I.T. | (41.79) | 67-51 |
| 12/30/09 | hosting | Charlotte | (54.82) | 56-54 |
| 01/03/10 | hosting | UMBC | (46.07) | 74-44 |
| 01/07/10 | at | Wake Forest | (53.74) | 63-66 |
| 01/14/10 | hosting | North Carolina | (56.55) | 79-64 |
| 01/18/10 | hosting | Virginia | (57.31) | 56-70 |
| 01/21/10 | at | Duke | (63.17) | 38-69 |
| 01/24/10 | at | Miami (FL) | (56.94) | 73-69 |
| 01/28/10 | hosting | Maryland | (55.90) | 44-60 |
| 01/31/10 | at | Georgia Tech | (56.52) | 47-61 |
| 02/05/10 | hosting | Wake Forest | (53.74) | 51-58 |
| 02/07/10 | at | N.C. State | (56.16) | 57-70 |
| 02/11/10 | hosting | Savannah St. | (37.14) | 68-41 |
| 02/14/10 | hosting | Duke | (63.17) | 53-65 |
| 02/18/10 | at | Florida St. | (61.07) | 68-78 |
| 02/21/10 | hosting | Boston Coll. | (57.38) | 69-64 |
| 02/25/10 | hosting | Clemson | (51.22) | 70-69 |
| 02/28/10 | at | Virginia | (57.31) | 46-55 |
| 03/04/10 | at | Boston Coll. | (57.38) | 49-62 |