| 09/03/05 | at | Eastern Kentucky | 24-16 |
| 09/10/05 | at | Kansas | 8-36 |
| 09/17/05 | hosting | Coastal Carolina | 30-3 |
| 09/24/05 | at | The Citadel | 45-13 |
| 10/08/05 | at | Furman | 31-34 |
| 10/15/05 | hosting | Georgia Southern | 24-7 |
| 10/22/05 | at | Wofford | 49-17 |
| 10/29/05 | hosting | Chattanooga | 35-25 |
| 11/05/05 | at | LSU | 0-24 |
| 11/12/05 | hosting | Western Carolina | 35-7 |
| 11/19/05 | at | Elon | 52-14 |
| 11/26/05 | hosting | Lafayette | 34-23 |
| 12/03/05 | hosting | Southern Illinois | 38-24 |
| 12/10/05 | hosting | Furman | 29-23 |
| 12/16/05 | vs. | Northern Iowa | 21-16 |