| 09/10/05 | at | John Carroll | 13-38 |
| 09/17/05 | hosting | DePauw | 12-38 |
| 09/24/05 | at | Wheaton | 7-48 |
| 10/01/05 | hosting | Kalamazoo | 38-7 |
| 10/08/05 | at | Olivet | 24-31 |
| 10/15/05 | hosting | Wisconsin Lutheran | 38-7 |
| 10/22/05 | hosting | Adrian | 42-21 |
| 10/29/05 | at | Albion | 0-34 |
| 11/05/05 | at | Tri-State | 42-10 |
| 11/12/05 | hosting | Alma | 38-20 |